Vac-Pac® Beats Milk Powder and Effervescent Products

Vac-Pac is a market-leading family of vaccine stabilizers by Animal Science Products that incorporates the latest technology to create more effective and easily used products that are more profitable for you.

he "Plus" in Vac-Pac® Plus is a rich, dark-blue dye that enables you to see the product not only in concentrated stock (as with traditional Vac-Pac), but in diluted drinking water as well.

EASIER TO USE

Vac-Pac Plus® offers many advantages, including:

• More concentrated formula dissolves more quickly than effervescent tablets or animal-derived milk proteins.
• Higher stabilizing power and solubility means quicker vaccine prep—no more of the 15-minute wait times of competing products. Our stabilizing action is immediate. The stabilized vaccine diluent is ready to receive the vaccine as soon as Vac-Pac Plus has been stirred into the solution.
• Advanced granulation technologies mean the same intense blue color in solution without all the dust.
• Available in packaging for both U.S. and international markets.

SAFER FOR VACCINES

he triple threat of oxidizers in water, pH imbalance and low tonicity can inactivate live vaccines, making them worthless. Vac-Pac Plus protects vaccines from this triple threat.

Vac-Pac Plus:

• Protects against oxidizers in much higher concentrations than found in water supplies.
• Absorbs shocks from occasional chlorine spikes. Research proves Vac-Pac Plus stabilizes sensitive vaccines in chlorinated water, retaining all of the original doses for over two hours.
• Contains a sophisticated buffering system that sustains an ideal pH climate for vaccines at about 7.8, regardless of whether the water used in the stock solution is acidic or alkaline. Several competitors ignore the vaccine's need for buffering and can actually worsen pH through their bubbling action ( Figure 8).

Vac-Pac® Beats Milk Powder and Effervescent Products

Vac-Pac is a market-leading family of vaccine stabilizers by Animal Science Products that incorporates the latest technology to create more effective and easily used products that are more profitable for you.

EASIER TO USE

Vac-Pac Plus® offers many advantages, including:

• Vac-Pac offers many advantages, including:
• A light red color enables the product to be seen in concentrated stock solutions (for use in diluted drinking water, please see our Vac-Pac® Plus product above).
• More concentrated formula dissolves more quickly than effervescent tablets or animal-derived milk proteins.
• Higher stabilizing power and solubility means quicker vaccine prep—no more of the 15-minute wait times of competing products. Our stabilizing action is immediate. The stabilized vaccine diluent is ready to receive the vaccine as soon as Vac-Pac Plus has been stirred into the solution.
• Advanced granulation technologies mean less dust.
• Packaged for the U.S. market.

SAFER FOR VACCINES

he triple threat of oxidizers in water, pH imbalance and low tonicity can inactivate live vaccines, making them worthless. Vac-Pac Plus protects vaccines from this triple threat.

Vac-Pac Plus:

• Protects against oxidizers in much higher concentrations than found in water supplies.
• Absorbs shocks from occasional chlorine spikes. Research proves Vac-Pac Plus stabilizes sensitive vaccines in chlorinated water, retaining all of the original doses for over two hours. Contains a sophisticated buffering system that sustains an ideal pH climate for vaccines at about 7.8, regardless of whether the water used in the stock solution is acidic or alkaline. Several competitors ignore the vaccine's need for buffering and can actually worsen pH through their bubbling action (SHO Figure 8).

e all know the advantages of spraying vaccines. Spray-Vac stabilizer, though, can make the process less expensive without reducing effectiveness. Before now, vaccine makers suggested using large amounts of expensive distilled water to deliver the spray, since they thought oxidizers like chlorine would inactivate the protection. With Spray-Vac, you'll be able to use local tap water. Besides saving you money, you may gain effectiveness in other ways, as research is now finding that distilled water's pH, low tonicity, and warmer temperatures can potentially hurt vaccines more than water with oxidants. Once you add even just 32 ml of Spray-Vac to each liter of cool tap water, you'll have a product that overcomes all these threats and makes an ideal solution for spray vaccines.

RESCUING SPRAY VACCINES FROM OXIDIZERS

Research by Lasher Associates proved that Spray-Vac rescues vaccines from oxidizers in water, making chlorinated tap water safe and effective.

In their experiment, a live freeze-dried infectious bronchitis vaccine was rehydrated in water alone, water containing Spray-Vac® Stabilizer, or chlorinated (4 and 8 ppm) water containing Spray-Vac® Stabilizer and then tested. Spray-Vac® Stabilizer had no deleterious effect on the bronchitis vaccine while chlorine at both concentrations inactivated as much as 80% of the virus. Further, Spray-Vac® Stabilizer completely rescued the vaccine from degradation by chlorine at both levels tested for as long as 2 hours.

Opti-Vac® eye-drop vaccine stabilizer gives you the advantages of drops—ensuring that every bird is immunized—while repairing the carrier to ensure maximum effectiveness.

hen eye-drop vaccines are rehydrated with distilled water or ordinary sterile diluent, they immediately lose large portions of their activity. Opti-Vac provides an environment that meets the vaccine's needs, preserving valuable titers drop after drop.

Rehydrated eye-drop vaccines must be stable for optimum potency and full immunity. Research (e.g., Toro et al., 1997) has demonstrated that a decline in eye-drop vaccine titers can reduce effectiveness. In one study, hens receiving a low-titer vaccine produced an immune response that was as poor as the birds that had received no vaccine at all ( Figure 1). Stabilizing eye-drop vaccines with Opti-Vac is an important step in preventing titer loss and ensuring that the first dose delivered is as potent as the last.

OPTIMUM PH FOR ANTIGEN SURVIVAL

• Unstable sterile diluents pose several hazards to live vaccines, including:
• Ordinary distilled water diluents are acidic by nature. This causes a rapid loss of vaccine titer after reconstitution.
• Vaccines that are diluted with an acidic diluent die rapidly, meaning most of the flock will not get the proper dose to develop good immunity. Because Opti-Vac eye-drop stabilizer keeps vaccines at the ideal pH, titers are maintained until the very last drop.

ISOTONIC ENVIRONMENT TO PROTECT VACCINE TITER

In addition to requiring a proper pH, many live vaccine antigens also require an isotonic environment, particularly fragile bacterial vaccines, such as Mycoplasmas. A USDA study compared vaccines diluted with isotonic Opti-Vac stabilizer to a typical hypotonic diluent to demonstrate this effect (Leigh et al., 2008).

Using Opti-Vac to rehydrate the vaccine prevented a loss of titer, preserving the full strength of each dose (Figure 2). The ordinary sterile diluent caused a 50-80% loss of the vaccines' titers when compared to vaccine rehydrated with Opti-Vac. Birds receiving the vaccine mixed with ordinary diluent would receive only 20-50% of the proper dose needed to develop a solid immune response.